Significant Reduction in Daily Hot Flash Frequency*
Multiple short- and long-term studies with ERr 731 (in over 400 peri- and postmenopausal women) confirm efficacy for menopausal symptom relief*
  • Well-designed clinical studies represent an unprecedented level of research in phytoestrogen approaches*
  • 2 multicenter, randomized, double-blind, placebo-controlled, phase III clinical trials (12 weeks)
  • 6-month prospective, post-marketing surveillance study in 70 gynecological centers
  • 1- and 2-year open observational studies to demonstrate long-term efficacy and predicted safety*

Efficacy comparable to hormone therapies*

  • In just 12 weeks, ERr 731 reduced median daily hot flashes by ~75%*†5
  • Similar to average 75% decrease with hormone therapies (HT)*6
  • Notably more effective than published clinical results with many other phytoestrogens and natural products*
Science Chart
In a 12-week study of 109 perimenopausal women, ERr 731 subjects reported a significant decrease in the median number of daily hot flashes compared to subjects taking placebo.*5
Science Chart
For comparison purposes, data were extrapolated from reviews of placebo-controlled studies of varying lengths.6,7

This estimated ratio is not included in the publication of a 12-week, multicenter, randomized, placebo-controlled clinical study of 112 postmenopausal women. It is calculated from the median change of 9 daily hot flashes divided by the median baseline value of 12 daily hot flashes.